Understanding The NALCN Sodium Channel Complex (P21482)

Target Name: NALCN sodium channel complex

NCBI ID: P21482

NALCN sodium channel complex

Other Name(s): UNC79-UNC80-NALCN cation channel complex

Understanding The NALCN Sodium Channel Complex

The NALCN sodium channel complex (UNC79-UNC80-NALCN cation channel complex) is a protein complex that plays a crucial role in the regulation of sodium (Na+) channels in various organisms, including humans. The NALCN complex is composed of three subunits: UNC79, UNC80, and NALCN. Each subunit of the NALCN complex has distinct functions, and the complex as a whole functions as a cation channel complex.

The NALCN complex is involved in various physiological processes in the body, including muscle and nerve function, neurotransmitter release, and inflammation. It is also a drug target and has been identified as a potential biomarker for various diseases, including cancer.

The UNC79 subunit of the NALCN complex is a type I transmembrane protein that contains a sodium channel. The UNC79 subunit is composed of an N-terminus that is involved in the formation of the N-terminal region of the channel, a catalytic center that is responsible for channel formation and stability, and a C-terminus that is involved in the formation of the cytoplasmic region of the channel.

The UNC80 subunit of the NALCN complex is a type II transmembrane protein that is involved in the regulation of the NALCN complex. The UNC80 subunit is composed of a N-terminus that is involved in the formation of the N-terminal region of the channel, a catalytic center that is responsible for channel formation and stability, and a C-terminus that is involved in the formation of the cytoplasmic region of the channel.

The NALCN complex functions as a cation channel complex by allowing the efficient passage of sodium ions through the channel. The NALCN complex is also involved in the regulation of other ions, including protons and k+ ions, and has been shown to play a role in the regulation of neurotransmitter release and muscle contractions.

The NALCN complex is a drug target of interest for various diseases, including cancer. Studies have shown that the NALCN complex is involved in the regulation of various cellular processes that are related to the development and progression of cancer. For example, studies have shown that the NALCN complex is involved in the regulation of cell proliferation, angiogenesis, and immune evasion.

In addition to its potential as a drug target, the NALCN complex is also a potential biomarker for various diseases. The NALCN complex is involved in the regulation of various physiological processes in the body, including muscle and nerve function, neurotransmitter release, and inflammation. Therefore, changes in the NALCN complex have been observed in various diseases, including cancer.

The NALCN complex is a complex protein that plays a crucial role in the regulation of sodium channels in various organisms, including humans. The NALCN complex is composed of three subunits: UNC79, UNC80, and NALCN. The UNC79 subunit is a type I transmembrane protein that contains a sodium channel, the UNC80 subunit is a type II transmembrane protein that is involved in the regulation of the NALCN complex, and the NALCN subunit is a type I transmembrane protein that is involved in the regulation of the NALCN complex.

Overall, the NALCN sodium channel complex (UNC79-UNC80-NALCN cation channel complex) is a protein complex that is involved in various physiological processes in the body. It is a potential drug target and has been identified as a potential biomarker for various diseases, including cancer. Further research is needed to fully understand the role of the NALCN complex in the regulation of sodium channels and its potential as a drug target and biomarker.

Protein Name: NALCN Sodium Channel Complex

The "NALCN sodium channel complex Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NALCN sodium channel complex comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets